With increasing antimicrobial resistance and the limited effectiveness of conventional antimicrobial agents, there is a growing interest in exploring alternative approaches to combat microbes. Phytochemicals have emerged as potential candidates for antimicrobial defense. They have long been recognized for their crucial roles in contributing to the defense mechanisms against pathogens and environmental stressors [1]. As humans consume plant-based foods and medicines, they can benefit from the bioactive compounds they contain. Scientific research has unraveled the multifaceted therapeutic potential of phytochemicals, highlighting their antimicrobial activity against bacteria, viruses, fungi, and other microorganisms [2]. One of the significant advantages of phytochemicals in antimicrobial defense is their broad-spectrum activity, which allows them to target multiple types of pathogens simultaneously [3]. This versatility is essential in combating infectious diseases that often involve mixed infections or evolved drug-resistant strains. By targeting various stages of microbial growth and replication, phytochemicals offer a multifaceted approach to tackling microbial infections.