Stereoelectroencephalography (SEEG) is a critical tool for localizing epileptogenic foci in patients with drug-resistant epilepsy. Traditional SEEG techniques, involving complex manual placement of multiple depth electrodes, pose challenges including lengthy operative times, increased radiation exposure, and the potential for human error leading to suboptimal electrode trajectories and complications. Robot-assisted SEEG electrode implantation has emerged as a transformative solution, leveraging robotic precision and advanced imaging integration to refine surgical planning and electrode placement, achieving accuracy and complication rates comparable to or better than those of manual methods. By achieving submillimeter accuracy and streamlining registration and trajectory execution, robotic platforms reduce operative time and radiation exposure while maintaining safety and efficacy. Incorporating multimodal imaging data, such as MRI, PET, and SPECT, enhances localization of seizure foci and critical functional areas, enabling targeted implantation that preserves essential brain functions.