Scholarlink

The neuraminidase (NA) glycoprotein of influenza virus plays a critical role in the release of progeny viruses and their spread, making it an important target for antiviral drugs. This chapter provides an overview of the structure and function of NA and of four NA inhibitors—zanamivir, oseltamivir, peramivir, and laninamivir—that are widely used for the treatment and prophylaxis of influenza A and B viral infections. The importance of monitoring the emergence and global spread of NA inhibitor-resistant viruses is also discussed.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Influenza Virus Neuraminidase Glycoprotein, Its Inhibitors, and Their Resistance

  • 章节

  • 发表日期：

    2026年

查看全文
  • Emi Takashita

摘要

The neuraminidase (NA) glycoprotein of influenza virus plays a critical role in the release of progeny viruses and their spread, making it an important target for antiviral drugs. This chapter provides an overview of the structure and function of NA and of four NA inhibitors—zanamivir, oseltamivir, peramivir, and laninamivir—that are widely used for the treatment and prophylaxis of influenza A and B viral infections. The importance of monitoring the emergence and global spread of NA inhibitor-resistant viruses is also discussed.