Fisheries management, climate change, and food security are critical issues for Sub-Saharan Africa. This chapter explores how effective fisheries management policies can mitigate the impacts of climate change on food security in the region. The study employs a quantitative methodology, utilizing secondary data on fish production, CO2 emissions, GDP per capita, population, urbanization, and governance. Data were collected from the Food and Agriculture Organization of the United Nations (FAO), the International Energy Agency (IEA), and the World Bank databases, covering the period from 2000 to 2020. The analysis involved descriptive statistics, multiple regression, mediation analysis using the Sobel test, and bootstrap methods with STATA/MP 18.0 software. The research included data from Sub-Saharan African countries, focusing on those with significant fisheries sectors. The results highlight the interdependence between climate change, fisheries management, and food security, with effective policies playing a crucial role in enhancing fish production and food security. The findings underscore the importance of integrated and sustainable approaches to address these global challenges, providing valuable insights for policy development and implementation in the region.