Children and adolescents are seen for mental health assessments in a wide variety of settings, ranging from community mental health centers and specialized behavioral health practices to their schools and family medicine clinics, to the juvenile justice system and family court, to crisis centers and psychiatric units. Each of these settings brings with it its own norms, values, beliefs, language, and behavioral expectations, shaping all aspects of the evaluations. In this chapter, we discuss four broad types of settings: outpatient settings (e.g., community mental health centers, private practices), integrated settings (e.g., schools, healthcare clinics, residential treatment centers), crisis settings (e.g., emergency rooms, mobile crisis teams, crisis lines), and legal or forensic settings (e.g., criminal court, family court, immigration court). For each type of setting, we discuss the broad goals of the mental health assessment, unique aspects of the clinician’s role, the procedures typically employed, the skills essential for conducting an effective assessment and communicating its findings, and ethical issues, along with other special considerations for a given setting. Case illustrations bring the unique aspects of each setting to life.