Pertussis, tetanus, and diphtheria pose a problems, especially pertussis in grown-ups. Whooping cough is increasing around the world, partially because the vaccine effectiveness weans off. Adults clinical presentation differ from the typical symptoms of children. It usually presents as a prolonged cough, its diagnose is many times missed and therefore htere is underreporting and delay in treatment, that does not avoid the spreading of the Bordetella. Pertussis is more severe in patients diagnosed of asthma or COPD. Vaccines are efficacious in its prevention. As the effectivity wanes off, there is a non universal recommendation to revaccinate older adults. Vaccination of the pregnant has an effectivity up to 90% to protect young babies, when the disease is more severe. Tetanus and diphtheria protection also fade, so adults need regular boosters. Older people especially might not have enough protection.