Breast imaging radiology plays a crucial role in the diagnosis and management of breast cancer. Understanding the basics of screening and diagnostic mammography, ultrasound, and breast MRI are important for any medical training. Indications for screening in average and high-risk women are reviewed. Details regarding positioning and acquisition of images, localization of findings, and the essentials of the Breast Imaging-Reporting and Data System (BI-RADS®) lexicon are provided. This chapter concludes with interesting facets on image-guided procedures. It is important to note the integral role that radiologists play in the multidisciplinary team and the imaging tools that radiologists use to detect breast cancer and guide surgical management.