This chapter provides an overview of pulmonary hypertension (PH) secondary to chronic lung disease (PH-CLD), focusing on mechanisms, prevalence, and assessment of right ventricular-pulmonary artery (RV-PA) coupling. It highlights the importance of RV-PA coupling in the prognostication of PH-CLD. Various methods for assessing RV-PA coupling, both invasive and non-invasive, are described, along with their limitations and implications for clinical practice. Further research is needed to investigate the prognostic significance of RV-PA coupling in PH-CLD and to explore the potential benefits of targeted therapies in this patient population.

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RV/PA Coupling in Pulmonary Hypertension Secondary to Chronic Lung Disease

  • Fatima Zeba,
  • Paul M. Heerdt,
  • Inderjit Singh

摘要

This chapter provides an overview of pulmonary hypertension (PH) secondary to chronic lung disease (PH-CLD), focusing on mechanisms, prevalence, and assessment of right ventricular-pulmonary artery (RV-PA) coupling. It highlights the importance of RV-PA coupling in the prognostication of PH-CLD. Various methods for assessing RV-PA coupling, both invasive and non-invasive, are described, along with their limitations and implications for clinical practice. Further research is needed to investigate the prognostic significance of RV-PA coupling in PH-CLD and to explore the potential benefits of targeted therapies in this patient population.