The aerospace industry is increasingly confronted with multifaceted challenges that require efficient, interdisciplinary collaboration. Concurrent Design Facilities (CDFs) offer an integrated environment that enables parallel development across domains, accelerating innovation cycles and enhancing system coherence. This study investigates the feasibility of establishing a specialized CDF to support the integration of Smart Automation (SA) in human health and safety applications for long-duration space missions. A targeted literature review is conducted to identify key medical technologies suitable for automation in space environments. Based on these insights, a CDF architecture is defined using a Model-Based Systems Engineering (MBSE) approach, enabling the structured implementation of Smart Automation through concurrent design processes tailored to mission-critical healthcare scenarios. The proposed framework demonstrates strong potential to enhance space mission planning and design, with possible extensions to other complex, safety-critical domains.