In this introductory chapter, we outline pivotal aspects of reflexivity and knowledge production in research processes, with a particular focus on migration studies. While there is broad consensus that reflexivity is essential for producing more nuanced, insightful, and socially responsible research, the ways in which we conceptualise and implement it in our everyday work as social scientists are far from straightforward. We begin by drawing on key understandings of reflexivity in the broader social sciences and humanities to highlight fundamental issues of knowledge production. We then examine how and why reflexivity has gained prominence in migration studies, addressing problematic epistemological underpinnings and specific challenges the field faces. Finally, we discuss how this volume contributes to debates on reflexivity and consider the work that remains to be done. In doing so, this chapter offers a programmatic approach to reflexivity and knowledge production, engaging with migration studies as a whole.