The contribution of different laryngeal disorders to changes in voice (dysphonia) and how they influence voice quality and laryngeal functions differs greatly. Voice-related biomarkers include clinical measures (e.g., modified GRBAS scale), some clinical diagnostic aids (e.g., voice handicap index), and additional instrumental measures (e.g., acoustic analysis and aerodynamics). Pathological changes in voice-related biomarkers could result from changes in the vocal folds (mass or tension), changes in infra- or supraglottic structures, or complex changes. Voice-related biomarkers are variables that serve as monitors of laryngeal pathologies in different health facilities with varying equipment levels. Biomarkers rely on clinicians, patients, or devices providing a variety of voice quality assessments and management for the benefit of patients and research. Some voice-related biomarkers can be used to overcome the limitations of others, such as the possibility of their use in severe dysphonia. Changes in biomarkers help clinicians determine their voice health plan or their research study design.