Here, we examine the current state and future directions of biobanking initiatives for preserving macroalgal biodiversity along the North American Pacific coast. We summarize the efforts of existing biobanking programs across non-profit organizations, academic institutions, and commercial entities, highlighting their diverse approaches to preserving brown and red macroalgae through both traditional culture-based methods and cryopreservation techniques. While several organizations are successfully maintaining gametophyte cultures, current biobanking efforts cover only a fraction of the region’s genetic diversity. We also highlight how understanding population genetics and local adaptation are important in the maintenance of regionally distinct germplasm collections. This chapter also explores the potential functional roles of microbial communities in macroalgal health and development, emphasizing the importance of preserving both host and microbiome for successful conservation, restoration, and aquaculture outcomes. Some key challenges we identified include limited geographical coverage, lack of standardization in preservation methods, and the need for greater coordination among biobanking facilities. We conclude by outlining key research priorities and advocating for standardized practices, while encouraging the expansion of biobanking initiatives along the Pacific coast.