Periprosthetic joint infection (PJI) is a relatively frequent and oftentimes devastating complication after total elbow arthroplasty (TEA). The reported rate of PJI after TEA is around 4%. Risk factors for the development of elbow PJI include rheumatoid arthritis, hypothyroidism, tobacco use disorder, steroid use, previous elbow surgery, and immunocompromised state. Possible treatments of PJI after TEA are arthrodesis, DAIR (debridement, antibiotics, and implant retention), one-stage revision, two-stage revision, and resection arthroplasty. The reported rates of eradication of PJI are 73% with two-stage, 71% with resection arthroplasty, 67% with one-stage, 58% with DAIR, and 40% with elbow arthrodesis.