With regard to the OAS Declaration of Inter-American Principles on Neurosciences, Neurotechnologies and Human Rights, approved in March 2023, and in addition to the recent ruling of the Chilean Supreme Court against the company that manufactures and markets neurotechnology devices, Guido Girardi v. Emotiv, of August 2023, it is necessary to establish regulatory criteria that clarify international standards on new advances in science and technology, always from a human rights perspective. There is a need to establish regulatory criteria that make clear international standards on new advances in science and technology, always with a human rights-based perspective. The challenges will be to generate reliable scenarios in the development of these new technologies, especially immersive technologies that use neurotechnology and artificial intelligence for the most vulnerable sectors, such as children and adolescents, genders and dissidences, and persons with disabilities, among others.