This paper proposes an approach to missing value imputation in a transcriptomic dataset using a self-organizing map. The self-organizing map is trained on a complete subset of the data. Instances with missing values are presented to the trained map and the best matching unit is used to impute the missing values in the instance. The empirical results show promise in the application of self-organizing maps for missing value imputation in transcriptomic datasets.

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Self-organizing Maps for Missing Value Imputation in Transcriptomic Datasets

  • Louzanne Swart,
  • Andries Engelbrecht,
  • Lyn-Marié Birkholtz

摘要

This paper proposes an approach to missing value imputation in a transcriptomic dataset using a self-organizing map. The self-organizing map is trained on a complete subset of the data. Instances with missing values are presented to the trained map and the best matching unit is used to impute the missing values in the instance. The empirical results show promise in the application of self-organizing maps for missing value imputation in transcriptomic datasets.