This chapter introduces the overarching theme and structure of the book Navigating AI in Business: Strategies and Insights Across Disciplines. It explores how artificial intelligence (AI) is reshaping the theory and practice of business administration, offering both unprecedented opportunities and complex challenges. While AI fosters innovation, efficiency, and new value-creation models, it raises urgent questions about ethics, governance, labor, and sectoral disruption. This chapter lays out the conceptual foundation for understanding the interplay between AI and strategic business processes, sets the stage for interdisciplinary dialogue, and provides an overview of the book’s four thematic parts, each addressing a critical dimension of AI adoption in the contemporary business landscape.