The pandemic outbreak of the novel coronavirus in late 2019 (COVID-19) resulted in heightened interest in a possible relationship between COVID-19 infection and myocarditis. Early reports suggested that up to 73% (Puntmann et al., JAMA Cardiol 5:1265–1273, 2020) of recovered COVID-19 patients had CMR evidence of myocarditis. A secondary infection related to COVID-19, most commonly occurring in pediatric patients, is MIS-C, which can include myocarditis among the spectrum of symptoms (Friedman and Son, COVID-19: multisystem inflammatory syndrome in children (MIS-C) clinical features, evaluation, and diagnosis). Late in 2020, vaccination against COVID-19 began in the general population, and vaccine-associated myocarditis (VAM) was also reported (Montgomery et al., JAMA Cardiol 6:1202–1206, 2021). This chapter will focus on three key features of CMR imaging and COVID-19. First, we will review the literature and imaging findings reported for COVID-19 myocarditis cases. Second, we will present and apply these imaging criteria to a case of myocarditis in a patient with MIS-C. Finally, we will present a case and review the imaging findings for a patient with VAM.