The safety of autonomous systems in dynamic and hazardous environments poses significant challenges. This paper presents a testing approach named SCALOFT for systematically assessing the safety of an autonomous uncrewed aerial vehicle in a mine. SCALOFT provides a framework for developing diverse test cases, real-time monitoring of system behaviour, and detection of safety violations. Detected violations are then logged with unique identifiers for detailed analysis and future improvement. SCALOFT helps build a safety argument by monitoring situation coverage and calculating a final coverage measure. We have evaluated the performance of this approach by deliberately introducing seeded faults into the system and assessing whether SCALOFT is able to detect those faults. For a small set of plausible faults, we show that SCALOFT is successful in this.