Ariquemes, located in the heart of the Brazilian Amazon in the state of Rondônia, faces a complex set of urban challenges that require innovative solutions. Historically plagued by deforestation, rapid land use change and infrastructure deficiencies, the city is grappling with the consequences of unbridled urbanization. This book chapter explores a proposed transformative urban planning system, the “15-Minute City,” tailored for Ariquemes. This concept seeks to reconfigure urban morphology and promote social inclusion, while addressing the environmental consequences of deforestation. By weaving accessible green spaces and essential services into the urban fabric, the concept aims to create a resilient, inclusive, and sustainable urban landscape. It is an integrative methodology that combines urban planning, community engagement, and sustainability principles. The results demonstrate the potential for the 15-Minute City planning in Ariquemes as a catalyst for social inclusion and green living. This project not only demonstrate the city’s ability to address these complex issues but also highlights the imperative of respecting Indigenous/minority rights and cultural heritage in the context of planning. The “Ariquemes 15-Minute City” stands as a beacon for the urban future through the adoption of the 15-Minute City concept for the urban planning system, proving that resilient and green urban living is within reach, even in the heart of the Amazon.