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This chapter highlights messenger RNA (mRNA) in revolutionizing vaccine technology using academic search engines such as PubMed, Google Scholar, and Scopus. The selected studies were systematically reviewed to emphasize the evolution and impact of mRNA vaccines. Current advancements in mRNA-based vaccines have demonstrated their efficacy in combating infectious diseases and cancers. The delivering mRNA encodes viral antigens into cells, producing antigenic proteins that trigger immune responses. Moreover, mRNA technology holds promising implications in treating diverse medical conditions such as cancers and genetic disorders. Despite these advancements, mRNA therapeutics face several challenges, including the stability of mRNA molecules, delivery challenges to target specific cells and adverse immune reactions. Several approaches are suggested to enhance mRNA stability through modified nucleosides and optimize delivery systems. In conclusion, mRNA can educate cells to produce proteins, vaccines, and therapeutics for preventive and curative medicine. Moreover, mRNA could act as a gene editing tool, a new disease treatment strategy.

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mRNA Vaccines as Member of Biotechnology-Based Vaccines

  • 章节

  • 发表日期：

    2026年

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  • Gamaleldin I. Harisa,
  • Maram M. Alzahrani

摘要

This chapter highlights messenger RNA (mRNA) in revolutionizing vaccine technology using academic search engines such as PubMed, Google Scholar, and Scopus. The selected studies were systematically reviewed to emphasize the evolution and impact of mRNA vaccines. Current advancements in mRNA-based vaccines have demonstrated their efficacy in combating infectious diseases and cancers. The delivering mRNA encodes viral antigens into cells, producing antigenic proteins that trigger immune responses. Moreover, mRNA technology holds promising implications in treating diverse medical conditions such as cancers and genetic disorders. Despite these advancements, mRNA therapeutics face several challenges, including the stability of mRNA molecules, delivery challenges to target specific cells and adverse immune reactions. Several approaches are suggested to enhance mRNA stability through modified nucleosides and optimize delivery systems. In conclusion, mRNA can educate cells to produce proteins, vaccines, and therapeutics for preventive and curative medicine. Moreover, mRNA could act as a gene editing tool, a new disease treatment strategy.