A large-scale additively manufactured (LSAM) or 3D printed model of the Pre-Contract DDG 51 class destroyer, internationally designated DTMB 5415 combatant, was tested for resistance in a calm-water towing-tank resistance test. The test results were compared to a geometrically similar model of the same length 5.720 m constructed of fiberglass to assess the accuracy and feasibility of LSAM models for future testing purposes. Appendages included propeller shafting, struts, bilge keels, and rudders. The models were measured dimensionally by laser scanning technology. The uncertainty in dimensions for the LSAM Model 5796 was 1.5 mm (0.061in) in comparison to 5.1 mm (0.20 in) for fiberglass Model 5617, or the LSAM version was over three (3) times better. Resistance results are reported at full scale. Typically, the relative differences in resistance between the two models were larger than the uncertainty estimates, but the differences were not likely from model dimensional differences. Future test results should be reported at model scale rather than full scale. Additionally, resistance tests should be performed with a bare hull for assessment of the added resistance from the appendages and comparison to existing international benchmark data that are for bare hull. In the future, model tests at a single speed should be repeated ten (10) times. A significant savings in cost and time-to-procure the model has been demonstrated. Model fabrication time was reduced from 20 weeks for fiberglass to 10 weeks for LSAM. LSAM is recommended for the manufacture of future calm-water towing-tank experimental models.