Autonomic business is not a distant vision; examples of it already exist in today’s businesses. In this chapter, we will explore these examples and provide insights into where the business opportunities to apply autonomic business (AB) are today. It is crucial for executives to understand AI agents and where they can add value to the business. While one may initially associate operational efficiencies with autonomic business, the most significant benefits in the long run will come from the changes to the business model that AI agents can effect. A diverse range of real-world cases is explored, from AI agents performing customer service tasks to robotic agents in EV factories to autonomous operations and business models in retail stores, railways, telecommunication networks and financial services.