Chemical “peeling” is when a chemical substance applied to the skin causes controlled destruction of the epidermis, whether or not it is part of the dermis, leading to skin renewal and reshaping. Chemical peeling is a noninvasive procedure in some skin diseases and cosmetic areas. It causes damage to the skin with different chemicals, allowing the skin to reshape and look younger. The first findings of this method were seen in Ancient Egyptian papyrus, and it was understood that the skin was tried to be repaired in various ways. Cleopatra taking milk baths and French women smoothing their skin with old wine show how ancient chemical peeling methods date back to ancient times. Occasionally, sour milk, stale wine, and animal fats have been used for skin regeneration. In recent years, alpha hydroxy acids (AHAs), which are very effective in keratinization disorders, have increased and have begun to be used frequently in many skin diseases and dermo-cosmetic areas. Chemical peeling aims to damage the skin layers to the desired depth and treat various lesions by taking advantage of wound healing during regeneration. Chemical peeling: It is used to treat a variety of skin lesions such as photodamage, pigment disorders, scars, and acne vulgaris.