Dentate mandible expansion and relative pre-jowl concavity are the two factors that lead to the development of jowls. Even though fat grafting along the lateral mandible posterior to the jowl can generate a young and angular jaw shape, considerable jowling necessitates surgical cervicofacial rhytidectomy. However, surgical lift of the jowl cannot address the geniomandibular groove. To achieve a smooth transition from the chin to the posterior mandible, fat grafting is required in this particular location. The lips become more delicate and lose their sharpness along the philtral columns as their age increases. Perioral rhytids are a manifestation of these alterations, which, when combined with subcutaneous fat atrophy, make it impossible for surgical rhytidectomy to be the sole treatment for the condition. Although resurfacing procedures are helpful, they are insufficient to correct perioral pucker lines independently. Instead, fat grafting to superficial compartments close to the vermillion-cutaneous interface is required to achieve volume augmentation of a perioral region that has been atrophied. On the other hand, the white roll and vermillion should be filled with injectables since the extent to which fat grafts are taken up in these places is not always predicted.