Both intrinsic and extrinsic factors affect how the chest ages. In most cases, a key factor is photoageing, and thus treatment commonly requires injectable fillers, skin peels and laser resurfacing in combination. There are specialists in treatmenting décolleté wrinkles who have published recommendations. In most individuals, the exposed upper portion of the chest, forming a V shape, sustains the effects of photoageing, which leads to the formation of rhytides, both superficial and deeper, together with alterations in the pigmentation of the skin and its texture. These changes may be felt to show a patient’s age in an unwelcome way. This site, as elsewhere on the body, is one where static and dynamic wrinkles co-exist, with the former being a result of solar damage and the latter due to repeated muscular contractions. Amongst non-invasive procedures practised in aesthetic medicine, the use of injectable botulinum toxin of serotype A (BoNT-A) is one of the most frequent. This toxin can prevent cholinergic neurotransmission by preventing the release of acetylcholine from the presynaptic terminal of neurons at the muscle end-plate. If rhytides form as a result of the contraction of particular muscles, injecting BoNT-A may weaken the muscle, resulting in softening of the wrinkles. This benefit may translate into a higher quality of life.