The African Continental Free Trade Area (AfCFTA) Agreement is one of the flagship initiatives of the African Union’s Agenda 2063’s first ten-year implementation plan. The full implementation of AfCFTA is equivalent to the establishment of a continental market, which would need concerted measures to decrease all trade costs and restrictions. The significance of banks in the successful development of the African economy, and hence in the expansion of the African economy, cannot be overstated. One of the most important functions of banks in Africa and other African economies is to provide the necessary capital to facilitate the establishment of businesses of all sizes in order to stimulate the economy’s development and growth. In this chapter, it will be argued that in the context of the AfCFTA, financial institutions, especially banks, play a key role in Africa’s trade finance policy execution. Banks offer the necessary financial assistance to promote intra-economic activity. They leverage businesses and have a financial mediation role aimed at ensuring the survival and success of businesses. However, the chapter will indicate the challenges which banks operating on the African continent are likely to face in their attempts to finance trade for purposes of driving forward the AfCFTA.