International trade and investment informed by the World Trade Organisation’s multilateral trade rules are essential for promoting economic growth and prosperity in today’s interconnected world. With a shared objective to make trade and investment more sustainable, efficient and attractive, the African Continental Free Trade Area (AfCFTA) adopted the Protocol on Investment in 2023. The AfCFTA’s Protocol on Investment has emerged on the global stage promising to reshape how nations engage in investment activities. The AfCFTA Investment Protocol may appear complex but, if efficiently implemented, its potential to foster economic development, encourage sustainable foreign investment and create new opportunities for the African continent can transform the international trade and investment landscape. The AfCFTA Investment Protocol aims at promoting, facilitating and protecting intra-African trade and investments. This is in line with its objective to create a single market through intra-African progressive trade liberalisation and, in turn, improve the business environment for Africa. This chapter introduces the AfCFTA and its significance to growing world trade as well as investment in Africa and the rest of the world. It points to the potential that the AfCFTA has in promoting inclusive growth in Africa and the rest of the world.