This paper presents the embodied carbon feasibility study of the University of Ottawa’s Civil Engineering building. The study explores potential options for replacing the current concrete structure with a modified design inspired by the University of Ottawa STM building. This comprehensive study primarily focuses on the structural system, examining and comparing embodied carbon of four distinct typologies: concrete, steel, hybrid-wood construction with concrete cores, and an all-wood construction with a timber lateral system. The focus of the study is a detailed structural system Life Cycle Assessment (LCA) that emphasizes environmental impact, particularly in relation to global warming potential. The research is geared towards understanding and evaluating the impact of carbon emissions, with a broader perspective on the concern over greenhouse gas emissions, notably CO2, and their contribution to climate change. The study’s findings underscore the potential for significant reductions in carbon emissions by incorporating timber and employing specific structural configurations. For example, opting for a timber structure with concrete shear walls could result in a potential reduction of carbon emissions by 29 and 43%, respectively, when compared to equivalent concrete and steel buildings. Moreover, substituting concrete shear walls with glulam-braced frames could lead to an additional 7% reduction in carbon emissions, underscoring the critical role of material selection in mitigating environmental impact.