Continuous application of fertilizers is necessary to maintain high yields in agricultural lands, as soil degradation can chronically reduce plant yield components. On the other hand, excessive fertilization leads to accumulation of soluble salts in the soil profile, increasing salinity and further reducing crop yield. Fertilizers containing high amounts of soluble salts, especially chloride and sodium ions, have a great potential to induce salinity. Use of saline water for irrigation purposes is another major driver of soil salinization. High salt content adversely impacts the soil environment and properties, causing salinity, osmotic, and oxidative stresses in plants. To avoid fertilization-induced salinity, an accurate management schedule is required for fertilizer application. Managing irrigation should also be considered, as fertilizers are typically applied through irrigation water. Selecting appropriate sources of fertilizers, particularly those with lower salinity, along with suitable application methods and frequencies, are crucial factors in achieving effective salinity management. Additionally, applying fertilizers based on soil testing results and utilizing drip irrigation systems play a pivotal role in optimizing salinity control.