In order to further control the operation status of the pipeline, and to provide reference for the later maintenance of the pipeline. This paper establishes the X65 double-point corrosion defective pipeline model, analyzes different axial spacing, annular spacing under the corrosion depth, corrosion length of the defective pipeline failure pressure change rule, puts forward a new double-point corrosion pipeline axial, annular failure pressure prediction model. The results show that: (1) Taking \(\lambda = {{\left| {P_{i + 1} - P_{i} } \right|} \mathord{\left/ {\vphantom {{\left| {P_{i + 1} - P_{i} } \right|} {P_{f} = 0.01}}} \right. \kern-0pt} {P_{f} = 0.01}}\) as the critical state criterion of two-point corrosion defect spacing, it is found that when the relative depth of corrosion is 0.4, the axial critical spacing of two-point corrosion defect is reached, that is, the critical value of spacing is 40 mm. (2) The annular distance has little change on the failure pressure, and the change range of failure pressure is 0.05–0.01 MPa, and the dimensionless failure pressure is close to 0 under each corrosion length. (3) Fitting the resulting failure pressure prediction model for different axial and annular spacing X65 class pipelines, the fitting coefficients were found to be 0.97805 and 0.99964, respectively. The results of this study can further inform the safe operation of pipelines.