In this work, copper vanadate (CuVA) and graphitic carbon nitride (g-C3N4) composite was fabricated for the removal of oxytetracycline (OTC). Different weight percent of CuVA (10 wt%, 30 wt% and 50 wt%) were successfully incorporated with g-C3N4 through wet chemical method and named as CV-10, CV-30 and CV-50, respectively. CuVA has a narrower bandgap energy compared to that of g-C3N4. The XRD results reveal the presence of g-C3N4 and CuVA in the composites, indicating that the composites were synthesised successfully. From the SEM images, g-C3N4 displayed a layered structure and it is composed by irregular particles. CuVA mainly consists of agglomerated nanoparticles while CV-30 was observed that the ash-like particles were incorporated on the surface of pebble shape particles. FTIR spectra showed that all the composites have Cu-O bending and V-O stretching. The stretching mode of C-N, C=N, N-H and N=H were found in g-C3N4 and CV-10. Stretching mode of C-N, C=N, N-H and N=H are barely observed for the CV-30 and CV-50 due to the high loading of CuVA. BET surface area showed that the CV-30 had a lower specific surface area and pore volume compared to that of pure g-C3N4. Throughout the removal of OTC, CV-30 achieved the highest efficiency (85.5%), followed by CV-50 (59.7%), CV-10 (54.3%), CuVA (45.1%) and g-C3N4 (13.9%). The scavenging experiment was carried out for CV-30 and the result showed that •O2− and h+ were the main active radicals in the photocatalytic degradation of OTC.