The Anthropocene confronts industrial design with unprecedented demands, reconciling human needs with ecological fragility, while attending to cultural plurality and ethical responsibility. This chapter examines how Bioneurodesign, an emerging approach rooted in neuroscience, human-centred thinking, and systemic awareness, can reframe design as an instrument for planetary wellbeing. Rather than replicating conventional models or merely proposing incremental improvements, the chapter advocates for a bioneuroethical shift. In this perspective, design becomes a medium for sensemaking, a way to process complexity, regenerate relationships across species, and respond meaningfully to uncertainty. Drawing on interdisciplinary sources, including cognitive science, posthuman ethics, and environmental philosophy, the chapter articulates a renewed theoretical foundation for design. Central to this inquiry is the idea that design operates between inner cognitive ecologies and outer material systems, shaping how individuals and societies interpret and inhabit the world. The proposal includes a manifesto that positions industrial design as an agent of coherence, emotional resilience, and adaptive transition. Ultimately, the chapter calls for a reimagining of design not as a tool for optimisation, but as a cultural and cognitive force, capable of mediating futures that are ecologically integrated, ethically grounded, and deeply human.