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This note provides an accessible introduction to key aspects of the mathematical modeling of brain fluid dynamics and solid mechanics in the context of brain glymphatics. We touch upon the different modes and cycles of brain pulsatility, the brain’s elastic properties, the brain’s fluid environment and fluid networks, and the chemical–mechanical interplay induced by osmotics, all under both physiological and pathological conditions.

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From brain physiology to brain physics

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  • 出版模式：

    开放获取

  • 发表日期：

    2026年

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  • Marie E. Rognes,
  • Kent-Andre Mardal,
  • Lars Magnus Valnes,
  • Vegard Vinje

摘要

This note provides an accessible introduction to key aspects of the mathematical modeling of brain fluid dynamics and solid mechanics in the context of brain glymphatics. We touch upon the different modes and cycles of brain pulsatility, the brain’s elastic properties, the brain’s fluid environment and fluid networks, and the chemical–mechanical interplay induced by osmotics, all under both physiological and pathological conditions.