Heart disease is the leading cause of mortality worldwide. Alongside medical treatments, psychological practices have become increasingly popular over the years due to their noninvasive nature and holistic benefits. Mindfulness, the practice of being present and nonjudgmental, focuses on situational awareness in managing stress. The technique involves assessing experiences from a neutral stance to improve self-confidence through kindness and compassion. Meditation can be used as part of a mindfulness practice, and the chapter gives examples of how to integrate these practices into your everyday life. When used with medical therapies, mindfulness-based treatments can help address innate psychological and physiological needs and improve heart disease management.