Rapid urbanization and industrialization in past few decades have led to substantial increase of manmade pollutants in water reservoirs that are difficult to biodegradation due to their synthetic origin. These pollutants are not only toxic to humans but also to the ecosystem. Several traditional wastewater treatment methods are available, but they are not effective against removal of heavy metals, synthetic dyes and other pollutants. Among enzymes, microbial laccases belong to a group of enzymes that have been used extensively for water purification and waste removal. However, soluble laccase faces several drawbacks that can be overcome by immobilization of the enzyme using appropriate support. Therefore, in this study, laccase was produced from indigenous bacterial strain. The enzyme production was also optimized to improve the yield of laccase. After that it was immobilized using silver nanoparticles. These nanoparticles were prepared and characterized using scanning electron microscopy (SEM), energy-dispersive electron microscopy (EDEX), and X-ray diffraction (XRD). Different immobilization parameters were also optimized. The thermal stability data showed that immobilized enzymes showed 80% residual activity at 50 °C after 4 h of incubation. Similarly, the storage stability profiling also exhibited that enzyme is stable for 1 month at room temperature. The reusability of laccase is also very higher, and it showed 96% activity even after 10 cycles. Immobilized laccases effectively lower the COD levels and BOD levels in wastewater. So, it can be concluded that silver nanoparticles immobilized laccase can be efficiently used in various bioreactors for continuous and sustainable purification of wastewater.