The first concept of a truly multifocal intraocular lens (IOL) was conceived in 1982 by Kenneth J. Hoffer, MD, in Santa Monica, CA, USA, following the examination of a patient with bilaterally decentered posterior chamber IOLs. Each optic was decentered such that the IOL optic only partially covered the pupil. The patient refracted to 20/25 (0.80) best corrected visual acuity (BCVA) with a standard refractive error and then did the same with a large aphakic (+10) refractive correction. The patient had no adverse symptoms (glare, haloes). This could only be explained by a concept of simultaneous image formation of two different foci where the brain is selecting the most beneficial image. This concept led to the fabrication by Iolab of the first multifocal IOL by slicing in half two different powered IOLs (an 18 D and a 21 D) and gluing the opposite halves together. This chapter describes the people involved who made this happen and the measures taken to get this concept accepted as well as how the fabricated Split Bifocal IOLs were finally implanted in two American patients in 1990 after cleaning and sterilization by Ioptex. No manufacturer became interested in following up with the idea until the author discovered the Oculentis Mplus bifocal IOL at the Paris European Society of Cataract & Refractive Surgery (ESCRS) Meeting in September 2010. This lens is almost an exact copy of the original Hoffer Split Bifocal and has had tremendous success in the EU by many respected surgeons. LensTec started making them in the USA (St. Pete Beach, FL) and received FDA approval of the design in 2022. This has proven that the original concept of brain selectivity from 1982 works. Many now refer to it as a “Split Bifocal”.

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Multifocal Intraocular Lenses: Historical Perspective

  • Kenneth J. Hoffer,
  • Giacomo Savini

摘要

The first concept of a truly multifocal intraocular lens (IOL) was conceived in 1982 by Kenneth J. Hoffer, MD, in Santa Monica, CA, USA, following the examination of a patient with bilaterally decentered posterior chamber IOLs. Each optic was decentered such that the IOL optic only partially covered the pupil. The patient refracted to 20/25 (0.80) best corrected visual acuity (BCVA) with a standard refractive error and then did the same with a large aphakic (+10) refractive correction. The patient had no adverse symptoms (glare, haloes). This could only be explained by a concept of simultaneous image formation of two different foci where the brain is selecting the most beneficial image. This concept led to the fabrication by Iolab of the first multifocal IOL by slicing in half two different powered IOLs (an 18 D and a 21 D) and gluing the opposite halves together. This chapter describes the people involved who made this happen and the measures taken to get this concept accepted as well as how the fabricated Split Bifocal IOLs were finally implanted in two American patients in 1990 after cleaning and sterilization by Ioptex. No manufacturer became interested in following up with the idea until the author discovered the Oculentis Mplus bifocal IOL at the Paris European Society of Cataract & Refractive Surgery (ESCRS) Meeting in September 2010. This lens is almost an exact copy of the original Hoffer Split Bifocal and has had tremendous success in the EU by many respected surgeons. LensTec started making them in the USA (St. Pete Beach, FL) and received FDA approval of the design in 2022. This has proven that the original concept of brain selectivity from 1982 works. Many now refer to it as a “Split Bifocal”.