This chapter offers practical advice for effectively planning and conducting hybrid learning, blending classroom and remote education. Hybrid learning seamlessly connects students in different locations, creating a flexible and adaptive learning environment that meets diverse student needs and psychological safety. A key focus is on fostering students’ active participation and responsibility in their own learning and development. The chapter emphasises the crucial role of educators, highlighting the importance of their advanced pedagogical skills. We explore the resources required to implement hybrid teaching, particularly those that enhance cognitive and socio-emotional interactions. This includes human-to-human interactions and interactions facilitated or enhanced by artificial intelligence (AI). The chapter provides structured guidelines for educators on designing and implementing hybrid teaching in higher education, ensuring that educators’ workload and well-being are considered. While the primary examples are drawn from health sciences, the principles and strategies discussed are applicable across various disciplines. By following the tips and strategies outlined in this chapter, educators can create a high-quality hybrid learning environment that benefits students and teachers. In addition to the hybrid model described in this chapter, we present future perspectives. By integrating AI tools, the model enhances interactions between humans and machines, supporting and enriching student learning experiences and students’ ability to effectively use AI tools.