The contribution is devoted to the study of issues related to the processes of innovative development of the transport logistics sector through the use of tools and technologies for digital transformation of modern business. The current state and general prospects for the development of the transport and logistics sector are considered, and the relevance and significance of innovative development of this sector of the economic system are emphasized. The advantages of innovative and digital transformation of the transport and logistics sector are identified. The goal of further development of modern transport logistics is defined and the features of this process, closely interconnected with the course of digitalization processes and the use of its tools in various sectors of the economy, are noted. General trends in the development of the transport logistics sector are identified, a list of the most promising areas of innovative development of the transport and logistics sector in the context of digital transformation is formed, and characteristics of the identified areas are given. Such modern trends in the development of the logistics sector as seamless and flexible logistics are mentioned. Conclusions are made on the state and further prospects for optimizing processes in the transport and logistics sector.