In order to further improve the analysis effect of regional economic coordinated growth, this paper puts forward a reliable regional economic coordinated growth strategy. This paper applies the computer spatial econometric method to regional economic analysis, and quantitatively estimates the direct and indirect effects of the spatial structure adjustment of each urban agglomeration (UA) on its economic growth (EG), and explores the different effects of the spatial structure evolution of UA such as population, industry and land use on EG. Finally, this paper puts forward a reliable regional economic coordinated growth strategy, which provides a basis for the spatial planning of UA in the new period.