In today’s increasingly interconnected and globalized world the goal of health protection cannot be achieved in isolation, namely by one country or an agency working alone, while no country can isolate itself from global health challenges and threats that transcend national boundaries and lay bare the restrictions of segmentation approaches. Without any doubt, the COVID-19 pandemic has vividly underscored how rapidly emerging infections can evolve, cost lives, adversely influence global travel and trade, and thus, the pressing need for the world to act together. It is within this context that health diplomacy could make a tangible contribution to securing and realizing global health as a global public good at all times and especially in the face of crises. In a changing global context, health diplomacy could serve as a bridge for building alliances on addressing health issues of common concern which require the cooperation of many countries and diverse actors and for ultimately promoting international cooperation for health. Against this backdrop, the chapter proposes a right to health approach to health diplomacy for identifying rights-based legal obligations within and beyond a State’s national borders, reflecting the weight of collective and concerted actions and the need for a standard-setting in a world that is full of tensions and challenges that concern our common future as global citizens.