This article delves into the themes of fictional androids and (im)mortality portrayed in Ridley Scott’s Blade Runner (1982) and the HBO television series Westworld (2016–2022) created by Lisa Joy and Jonathan Nolan. Throughout the history of cinema, there has been a significant presence of robots, a theme that has been explored in various ways such as the “Maschinenmensch” from the 1927 film Metropolis directed by Fritz Lang, or the recent high-tech Ava from the 2014 film Ex Machina directed by Alex Garland. Given the emergent interest in an interdisciplinary perspective of the relationship between films, AI, and death, I propose a posthuman thanato-film analysis of complex AI characters such as replicant Roy in Blade Runner and hosts Dolores and Maeve in Westworld as representations of self-aware AI androids. This selection is driven by two main reasons: firstly, film itself acts as a cognitive apparatus, prompting viewers to engage with its ideas and perspectives, often transcending individual human thought, and secondly, the depiction of androids as sentient beings within the cinematic realm serves as a direct exploration of mortality and the existential contemplation of death. Therefore, the objective of this article is to explore a potential intersection between film and AI regarding the themes of death and (im)mortality. This exploration aims to investigate the relevance of the concept of death to fictional android machines, which serve as innovative entities capable of interaction and learning. These machines not only exhibit seemingly eternal qualities but also possess the capability to terminate the lives of other living beings.