This paper studies the influence of interactive artificial intelligence (AI) system on English learners’ autonomous learning ability. Through the investigation of college students, this paper compares and analyzes the differences in learning behavior, academic achievement and user experience between the experimental group (EG) using interactive AI system and the control group (CG) not receiving this intervention. Research results reveal that EG participants not only show significantly longer study time and better academic performance but also express high satisfaction with the interactive AI system. The system is recognized for providing individualized learning experience, timely feedback and effective educational support. The above findings show that the interactive AI system can not only effectively attract English learners but also improve their learning effectiveness and user satisfaction. So, educators should integrate such systems to build a customized and efficient English learning environment, thus promoting English education quality and cultivating learners’ autonomy.