Ensuring desirable level of food and nutrition securities for the growing population amidst undeniable climate changeClimate change impacts and shrinkingShrinking natural resources base is an overwhelming challenge in arid land countries. There are ample indications that the global food production might not keep up the pace with escalating populationEscalating population growth and, several countries in theArid arid region, Gulf Cooperation Council countries in particular, will continue to rely on significant food import. Furthermore, any disruption in the food supply chain will have significant, sudden negative consequences on food and nutritional securities. Water scarcityWater scarcity, land degradation, and soil salinization are rendering more agricultural lands unproductive every year. A reliable data suggested that nearly 2000 ha irrigated land is abandoned on a daily basis in 75 countries due to soil salinity alone. The current systems of food production in the arid region are not aligned with available resources or prevailing climatic conditions. The development and adoption of innovative, climate-resilientResilient agri-food production systems are crucial to produce food sustainably without endangering the environment or the natural resource base of theArid arid countries. In this context, farmers are now shifting to alternative production systems like controlled environment agricultureAgriculture, where they can grow crops with limited quantities of potable water and irrespective of prevailing climatic conditions. This chapter presents a comprehensive review of current agricultural practices and several steps already initiated or required to be implemented to advance towards regenerativeRegenerative, low-emission agri-food production systems contributing to food securityFood security and a sustainable future for everyone who relies on agriculture. The use of newer communication, data gathering, data handling, and artificial intelligence technologies can assist farmers to make right decisions to ensure resources conservation and enhance efficiency and sustainabilitySustainability of food production systems.