“Care of the Pediatric Solid Organ Transplant Recipient” provides details on the unique considerations in managing pediatric patients who have undergone solid organ transplantation. This guide emphasizes the critical role of primary care providers (PCPs) in ensuring continuity of care, from pre-transplant preparation to long-term post-transplant management. Key topics include the importance of vaccination, growth and nutrition monitoring, and the psychosocial aspects of pediatric transplantation. This chapter also addresses the management of common complications such as infections, rejection, and malignancies and highlights the significance of early intervention and routine follow-up. Additionally, it covers the transition of care from pediatric to adult healthcare systems, focusing on strategies to support adolescents and young adults in maintaining adherence and achieving successful long-term outcomes. This chapter aims to enhance the quality of life and overall health of pediatric solid organ transplant recipients.