Cardiovascular diseases pose a significant public health challenge, particularly among young populations where early risk detection remains crucial. This study proposes using interpretable machine learning models for assessing cardiovascular risk in young Mexican adults using anthropometric, biochemical, and hematological biomarkers, focusing on homocysteine as a key metabolic indicator. We propose a hierarchical diagnostic approach comparing four decision tree algorithms (J48, CART, CHAID*, and SPAARC), prioritizing model explainability for clinical decision support. Our analysis identifies SPAARC as the best-balanced algorithm, maintaining diagnostic accuracy while preserving interpretability, critical for screening asymptomatic youth where traditional tools underperform. These findings provide a framework for developing adapted preventive tools in underrepresented populations.

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Decision Trees as a Support Tool for the Early Diagnosis of Cardiovascular Diseases in Young Individuals

  • Abraham Carrasco Barradas,
  • Marisol Cruz Ramírez,
  • Handry Serrano Fabela,
  • Abraham Barradas Cortés,
  • Daniela Ortega Juárez,
  • Rafael Rivera López,
  • Nayeli Salomé Barrios Cruz,
  • Erick de la Cruz Hernández

摘要

Cardiovascular diseases pose a significant public health challenge, particularly among young populations where early risk detection remains crucial. This study proposes using interpretable machine learning models for assessing cardiovascular risk in young Mexican adults using anthropometric, biochemical, and hematological biomarkers, focusing on homocysteine as a key metabolic indicator. We propose a hierarchical diagnostic approach comparing four decision tree algorithms (J48, CART, CHAID*, and SPAARC), prioritizing model explainability for clinical decision support. Our analysis identifies SPAARC as the best-balanced algorithm, maintaining diagnostic accuracy while preserving interpretability, critical for screening asymptomatic youth where traditional tools underperform. These findings provide a framework for developing adapted preventive tools in underrepresented populations.