The construction sector is a significant consumer of natural resources and a major contributor to energy consumption, leading to considerable environmental repercussions that have raised serious concerns. This study seeks to enhance the process of selecting building materials, given the adverse effects that many conventional construction materials impose on the environment. Certain materials utilized in building construction are associated with elevated levels of Embodied Energy (EE) and Carbon Dioxide (CO2) emissions, necessitating the identification of more sustainable and environmentally friendly alternatives to foster a healthier future. Furthermore, this research includes a comparative analysis of three houses constructed with varied materials: a standard burnt brick house, a cement block house, and a mudbrick house. A mixed-methods approach was utilized to quantify each construction technique's EE and CO2 emission. After thorough evaluation, three houses of similar floor area and exposed to identical climatic conditions were chosen for the study. The findings revealed that the mudbrick house (House 2) emerged as the most sustainable option, primarily since mudbrick generates no EE or CO2 emissions. In contrast, materials such as cement blocks, steel, concrete, and aluminum were found to significantly contribute to environmental degradation and toxicity. This research advocates for a practical framework for the adoption of alternative building materials in residential construction, emphasizing the urgent need for decisive actions to combat climate change and promote sustainability.