This study examines the scientific contributions of the Higher Institute of Accounting and Administration at the University of Aveiro (ISCA-UA) from 2019 to 2022, focusing on how these align with Education 5.0 and Society 5.0 goals. Using a case study approach, data were collected from institutional records, analyzing publications by type and thematic focus, emphasizing areas that promote societal well-being, multiliteracy, and educational innovation. The methodology involves a mixed-methods approach: quantitative analysis assesses publication trends, distribution by faculty rank, and output frequency, while qualitative analysis identifies themes relevant to societal and educational advancements. This approach provides insights into how ISCA-UA’s research aligns with Education 5.0 objectives, fostering both technical and socio-emotional skills needed for a “super-smart” society. Findings highlight an increase in publications addressing digital transformation, sustainability, and governance, reflecting the institution’s adaptability and responsiveness to societal shifts, particularly noticeable during the COVID-19 pandemic. This emphasis supports Education 5.0s aims of preparing students with versatile skills for modern challenges. The study contributes to the academic literature by showing how higher education institutions can align research outputs with global educational frameworks, promoting interdisciplinary skills and social responsibility. Future research could explore the impact of these themes on curriculum design and student development, further supporting the evolution toward Education 5.0.