Delivering high quality healthcare is a complex endeavour, involving the retrieval, sharing, and analysis of large quantities of data. It requires collaboration between a team of skilled practitioners, the assimilation of enormous volumes of medical knowledge, and reliably effective decision making. To achieve this, clinical systems must be able to integrate a mountain of data from different sources and somehow present the right information to clinicians and other decision makers—at the right time and place and in a language that is meaningful to the user. When implemented effectively, SNOMED CT® supports clinical systems in achieving these goals, thereby enabling optimal health outcomes for patients, effective delivery of health services, and innovative clinical research. This chapter explores the benefits of SNOMED CT® to healthcare and its important role in data interoperability.