The liver, as a major reticuloendothelial organ, can be a primary site of lymphoma or involved secondarily by hematologic neoplasms originating elsewhere. It is crucial for liver pathologists, who often encounter these specimens first, to recognize abnormal lymphocytosis and initiate appropriate diagnostic workup. Although clinical presentation and imaging manifestation of hepatic lymphomas are variable and nonspecific, their management and prognosis are significantly different from other non-hematologic malignancies. This chapter reviews the most common hepatic lymphomas, detailing their clinical presentations, imaging findings, histopathologic features, major differential diagnoses, and the diagnostic challenges involved. Accurate diagnosis and management of hematologic neoplasms in the liver often require close collaboration between liver pathologists and hematopathologists. Early diagnosis and interprofessional collaboration are essential for improving survival outcomes in patients with hepatic hematologic neoplasms. Additionally, further research is necessary to advance our understanding of the underlying pathophysiology.