This study arises from the need for cardiologists to understand the fluid dynamics of coronary stents in order to find the most suitable stent for each specific clinical case. The stenosis of the coronary arteries is a very widespread pathological situation. More and more, the tendency is to intervene with the implantation of stents rather than with bypasses. The stent has many advantages over the bypass: a higher probability of success and less invasiveness of the intervention. The failure of cardiovascular device implants is attributed to haemodynamic factors, such as blood flow stagnation and low wall shear stress (WSS). It is also hypothesized that blood flow stasis and fluid vein detachment favour intimal hyperplasia, atherosclerosis and thrombus formation, all causes of implant failure. A device should, therefore, be designed in such a way as to prevent adverse fluid dynamic conditions associated with implant failure. Hence, the need to be able to know in detail the fluid dynamic response of stents.

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Numerical Newtonian Thermo-Haemo-Dynamics (THD) in Coronary Stents

  • Mattia Amitrano,
  • Andrea Boghi,
  • Fabio Gori Ammannati

摘要

This study arises from the need for cardiologists to understand the fluid dynamics of coronary stents in order to find the most suitable stent for each specific clinical case. The stenosis of the coronary arteries is a very widespread pathological situation. More and more, the tendency is to intervene with the implantation of stents rather than with bypasses. The stent has many advantages over the bypass: a higher probability of success and less invasiveness of the intervention. The failure of cardiovascular device implants is attributed to haemodynamic factors, such as blood flow stagnation and low wall shear stress (WSS). It is also hypothesized that blood flow stasis and fluid vein detachment favour intimal hyperplasia, atherosclerosis and thrombus formation, all causes of implant failure. A device should, therefore, be designed in such a way as to prevent adverse fluid dynamic conditions associated with implant failure. Hence, the need to be able to know in detail the fluid dynamic response of stents.